| Short Description : | Rabbit polyclonal anti-Serine/threonine-protein kinase MAK (126-175 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAK |
| Gene ID: | 4117 |
| Uniprot ID: | MAK_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MAK at the amino acid range 126-175 |
| Immunogen Region: | 126-175 aa |
| Specificity: | MAK Polyclonal Antibody detects endogenous levels of MAK protein. |
| Post Translational Modifications | Autophosphorylated. Phosphorylated on serine and threonine residues. |
| Function | Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors. Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells. |
| Protein Name | Serine/Threonine-Protein Kinase MakMale Germ Cell-Associated Kinase |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleMidbodyCell ProjectionCiliumPhotoreceptor Outer SegmentPhotoreceptor Inner SegmentLocalized In Both The Connecting Cilia And The Outer Segment AxonemesLocalized Uniformly In Nuclei During InterphaseTo The Mitotic Spindle And Centrosomes During Metaphase And AnaphaseAnd Also To Midbody At Anaphase Until Telophase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Mak antibodyAnti-Male Germ Cell-Associated Kinase antibodyAnti-MAK antibody |
Information sourced from Uniprot.org
