Anti-MAGEA6 antibody [SAA1840] (STJA0020268)

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STJA0020268
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Melanoma-Associated antigen 6 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1840
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: MAGEA6
Gene ID: 4105
Uniprot ID: MAGA6_HUMAN
Post Translational Modifications Ubiquitinated by the DCX(DCAF12) complex specifically recognizes the diglutamate (Glu-Glu) at the C-terminus, leading to its degradation.
Function Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.
Protein Name Melanoma-Associated Antigen 6
Cancer/Testis Antigen 1.6
Ct1.6
Mage-6 Antigen
Mage3b Antigen
Alternative Antibody Names Anti-Melanoma-Associated Antigen 6 antibody
Anti-Cancer/Testis Antigen 1.6 antibody
Anti-Ct1.6 antibody
Anti-Mage-6 Antigen antibody
Anti-Mage3b Antigen antibody
Anti-MAGEA6 antibody
Anti-MAGE6 antibody

Information sourced from Uniprot.org

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