Anti-MAGEA4 antibody (28-317) (STJ113212)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MAGEA4 (28-317) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MAGEA4 |
| Gene ID | 4103 |
| Uniprot ID | MAGA4_HUMAN |
| Immunogen Region | 28-317 |
| Immunogen Sequence | AQAPTTEEQEAAVSSSSPLV PGTLEEVPAAESAGPPQSPQ GASALPTTISFTCWRQPNEG SSSQEEEGPSTSPDAESLFR EALSNKVDELAHFLLRKYRA KELVTKAEMLERVIKNYKRC FPVIFGKASESLKMIFGIDV KEVDPASNTYTLVTCLGLSY DGLLGNNQIFPKTGLLIIVL GTIAMEGDSASEEEIWEELG VMGVYDGREHTVYGEPRKLL TQDWVQENYLEYRQVPGSN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 28-317 of human MAGEA4 (NP_002353.3). |
Additional Info
| Tissue Specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. |
| Function | Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis. |
| Protein Name | Melanoma-Associated Antigen 4Cancer/Testis Antigen 1.4Ct1.4Mage-4 AntigenMage-41 AntigenMage-X2 Antigen |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Melanoma-Associated Antigen 4 antibodyAnti-Cancer/Testis Antigen 1.4 antibodyAnti-Ct1.4 antibodyAnti-Mage-4 Antigen antibodyAnti-Mage-41 Antigen antibodyAnti-Mage-X2 Antigen antibodyAnti-MAGEA4 antibodyAnti-MAGE4 antibody |
Information sourced from Uniprot.org