• Western blot analysis of Mouse brain, using MAFA Rabbit polyclonal antibody (STJ11103900) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-MAFA antibody (269-353) (STJ11103900)

SKU:
STJ11103900

$151.88 - $705.38
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcription Factor Mafa (269-353) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAFA
Gene ID: 389692
Uniprot ID: MAFA_HUMAN
Immunogen Region: 269-353
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 269-353 of human MAFA (NP_963883.2).
Immunogen Sequence: QSCRFKRVQQRHILESEKCQ LQSQVEQLKLEVGRLAKERD LYKEKYEKLAGRGGPGSAGG AGFPREPSPPQAGPGGAKGT ADFFL
Tissue Specificity Expressed in the islets of Langerhans (at protein level).
Post Translational Modifications Ubiquitinated, leading to its degradation by the proteasome. Phosphorylated at tyrosines.
Function Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence.
Protein Name Transcription Factor Mafa
Pancreatic Beta-Cell-Specific Transcriptional Activator
Ripe3b1 Factor
V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A
Database Links Reactome: R-HSA-210745
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Mafa antibody
Anti-Pancreatic Beta-Cell-Specific Transcriptional Activator antibody
Anti-Ripe3b1 Factor antibody
Anti-V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A antibody
Anti-MAFA antibody

Information sourced from Uniprot.org

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