Anti-MAdCAM-1 antibody [17F5] (STJ16101936)

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STJ16101936-02
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Host: Mouse
Applications: ELISA/FC/IHC-P/WB
Reactivity: Human/Camel
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-MAdCAM-1 is suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : 17F5
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS with <0.1% sodium azide
Purification: Purified
Concentration: 1 mg/mL
Storage Instruction: Store aliquots at-20°C, and thawed aliquots at 2-8°C.
Immunogen: Recombinant soluble MAdCAM-1-fc fusion protein
Background Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a ~60 kDa transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyer s patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7) , CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking, Mouse anti Human MAdCAM-1 antibody, clone 17F5 recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1 (Leung, E. et al. 2004).

Information sourced from Uniprot.org

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