| Background | Macrophages are a type of white blood cell present in essentially all tissues, functioning in host defense via phagocytosis and pinocytosis. Macrophages digest and present antigens to T-and B-lymphocytes, and also work to secrete complement components, coagulation factors, many regulatory molecules including interferon and interleukin 1, as well as some prostaglandins and leukotrienes. Macrophages are associated with a large proportion of malignant tumours, and have been reported as a promising target for cancer therapies due to their angiogenesis-promoting and trophic roles. Anti Macrophage, also known as HAM-56, detects tingible body macrophages found in the germinal centers of lymph nodes, as well as a subpopulation of endothelial cells, namely those of the capillaries and smaller blood vessels. Anti-Macrophage also reacts with interdigitating macrophages of lymph nodes and tissue macrophages, Kupffer cells of the liver, and alveolar macrophages of the lung. |
Information sourced from Uniprot.org
![Anti-Macrophage antibody [EP-3] (STJ16100761)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/149478/302382/STJ16100761_1__92883.1646940567.jpg?c=1 "Anti-Macrophage antibody [EP-3] (STJ16100761)")