Anti-Macrophage antibody [IHC618] (STJA0042207)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
General Information
| Short Description | Mouse monoclonal anti-Macrophage for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC618 |
| Conjugation | Unconjugated |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Specificity | Tested and validated on tonsil tissue. |
Additional Info
| Background | Macrophages are a type of white blood cell present in essentially all tissues, functioning in host defense via phagocytosis and pinocytosis. Macrophages digest and present antigens to T-and B-lymphocytes, and also work to secrete complement components, coagulation factors, many regulatory molecules including interferon and interleukin 1, as well as some prostaglandins and leukotrienes. Macrophages are associated with a large proportion of malignant tumours, and have been reported as a promising target for cancer therapies due to their angiogenesis-promoting and trophic roles. Anti Macrophage, also known as HAM-56, detects tingible body macrophages found in the germinal centers of lymph nodes, as well as a subpopulation of endothelial cells, namely those of the capillaries and smaller blood vessels. Anti-Macrophage also reacts with interdigitating macrophages of lymph nodes and tissue macrophages, Kupffer cells of the liver, and alveolar macrophages of the lung. |
Information sourced from Uniprot.org