| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Metastasis-associated in colon cancer protein 1 (411-460 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MACC1 |
| Gene ID: | 346389 |
| Uniprot ID: | MACC1_HUMAN |
| Immunogen Region: | 411-460 aa |
| Specificity: | MACC1 Polyclonal Antibody detects endogenous levels of MACC1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1 at the amino acid range 411-460 |
| Function | Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. |
| Protein Name | Metastasis-Associated In Colon Cancer Protein 1Sh3 Domain-Containing Protein 7a5 |
| Cellular Localisation | CytoplasmNucleusMainly Found In The Cytoplasm In Non-Metastasizing Tumors |
| Alternative Antibody Names | Anti-Metastasis-Associated In Colon Cancer Protein 1 antibodyAnti-Sh3 Domain-Containing Protein 7a5 antibodyAnti-MACC1 antibody |
Information sourced from Uniprot.org