| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Lymphotoxin alpha for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R08-7H6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | LTA |
| Gene ID: | 4049 |
| Uniprot ID: | TNFB_HUMAN |
| Immunogen: | A synthesized peptide derived from human TNF beta |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
| Protein Name | Lymphotoxin-AlphaLt-AlphaTnf-BetaTumor Necrosis Factor Ligand Superfamily Member 1 |
| Database Links | Reactome: R-HSA-5668541Reactome: R-HSA-5669034Reactome: R-HSA-5676594 |
| Cellular Localisation | SecretedMembraneThe Homotrimer Is SecretedThe Heterotrimer Is Membrane-Associated |
| Alternative Antibody Names | Anti-Lymphotoxin-Alpha antibodyAnti-Lt-Alpha antibodyAnti-Tnf-Beta antibodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 1 antibodyAnti-LTA antibodyAnti-TNFB antibodyAnti-TNFSF1 antibody |
Information sourced from Uniprot.org