| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LY86 (21-162) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LY86 |
| Gene ID: |
9450 |
| Uniprot ID: |
LY86_HUMAN |
| Immunogen Region: |
21-162 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 21-162 of human LY86 (NP_004262.1). |
| Immunogen Sequence: |
GGGGKAWPTHVVCSDSGLEV LYQSCDPLQDFGFSVEKCSK QLKSNINIRFGIILREDIKE LFLDLALMSQGSSVLNFSYP ICEAALPKFSFCGRRKGEQI YYAGPVNNPEFTIPQGEYQV LLELYTEKRSTVACANATIM CS |
| Tissue Specificity | Highly expressed in B-cells, monocytes and tonsil. |
| Function | May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. |
| Protein Name | Lymphocyte Antigen 86Ly-86Protein Md-1 |
| Database Links | Reactome: R-HSA-166016 |
| Cellular Localisation | SecretedExtracellular SpaceAssociated With Cd180 At The Cell Surface |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 86 antibodyAnti-Ly-86 antibodyAnti-Protein Md-1 antibodyAnti-LY86 antibodyAnti-MD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
