| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LY75 (216-1722) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LY75 |
| Gene ID: |
100526664/4065 |
| Uniprot ID: |
LY75_HUMAN |
| Immunogen Region: |
216-1722 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 216-1722 of human LY75 (NP_002340.2). |
| Immunogen Sequence: |
CEDNWEKNEQFGSCYQFNTQ TALSWKEAYVSCQNQGADLL SINSAAELTYLKEKEGIAKI FWIGLNQLYSARGWEWSDHK PLNFLNWDPDRPSAPTIGGS SCARMDAESGLWQSFSCEAQ LPYVCRKPLNNTVELTDVWT YSDTRCDAGWLPNNGFCYLL VNESNSWDKAHAKCKAFSSD LISIHSLADVEVVVTKLHNE DIKEEVWIGLKNINIPTLFQ WSDGTEVTLTYWDENEPNV |
| Tissue Specificity | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. |
| Protein Name | Lymphocyte Antigen 75Ly-75C-Type Lectin Domain Family 13 Member BDec-205Gp200-Mr6Cd Antigen Cd205 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 75 antibodyAnti-Ly-75 antibodyAnti-C-Type Lectin Domain Family 13 Member B antibodyAnti-Dec-205 antibodyAnti-Gp200-Mr6 antibodyAnti-Cd Antigen Cd205 antibodyAnti-LY75 antibodyAnti-CD205 antibodyAnti-CLEC13B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
