• Western blot analysis of various lysates, using LY75 antibody (STJ112105) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-LY75 antibody (216-1722) (STJ112105)

SKU:
STJ112105

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LY75 (216-1722) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LY75
Gene ID: 100526664/4065
Uniprot ID: LY75_HUMAN
Immunogen Region: 216-1722
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 216-1722 of human LY75 (NP_002340.2).
Immunogen Sequence: CEDNWEKNEQFGSCYQFNTQ TALSWKEAYVSCQNQGADLL SINSAAELTYLKEKEGIAKI FWIGLNQLYSARGWEWSDHK PLNFLNWDPDRPSAPTIGGS SCARMDAESGLWQSFSCEAQ LPYVCRKPLNNTVELTDVWT YSDTRCDAGWLPNNGFCYLL VNESNSWDKAHAKCKAFSSD LISIHSLADVEVVVTKLHNE DIKEEVWIGLKNINIPTLFQ WSDGTEVTLTYWDENEPNV
Tissue Specificity Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Post Translational Modifications N-glycosylated.
Function Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes.
Protein Name Lymphocyte Antigen 75
Ly-75
C-Type Lectin Domain Family 13 Member B
Dec-205
Gp200-Mr6
Cd Antigen Cd205
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Lymphocyte Antigen 75 antibody
Anti-Ly-75 antibody
Anti-C-Type Lectin Domain Family 13 Member B antibody
Anti-Dec-205 antibody
Anti-Gp200-Mr6 antibody
Anti-Cd Antigen Cd205 antibody
Anti-LY75 antibody
Anti-CD205 antibody
Anti-CLEC13B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance