| Short Description : | Goat polyclonal antibody anti-LSP1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 50kDa band observed in Human Peripheral Blood Mononucleocytes, (PBMs) and Tonsil lysates and in lysates of cell line Daudi, and approx. 50-55kDa in Human Tonsil and Mouse Spleen |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | LSP1 |
| Gene ID: | 4046 |
| Uniprot ID: | LSP1_HUMAN |
| Accession Number: | NP_002330.1; NP_001013271.1 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | RYKFVATGHGKYEKV |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_002330.1; NP_001013271.1). Reported variants represent identical protein: NP_001013273.1, NP_001013271.1, NP_001013272.1 |
| Post Translational Modifications | Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis. |
| Function | May play a role in mediating neutrophil activation and chemotaxis. |
| Protein Name | Lymphocyte-Specific Protein 147 Kda Actin-Binding Protein52 Kda PhosphoproteinPp52Lymphocyte-Specific Antigen Wp34 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Lymphocyte-Specific Protein 1 antibodyAnti-47 Kda Actin-Binding Protein antibodyAnti-52 Kda Phosphoprotein antibodyAnti-Pp52 antibodyAnti-Lymphocyte-Specific Antigen Wp34 antibodyAnti-LSP1 antibodyAnti-WP34 antibody |
Information sourced from Uniprot.org
