| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-LRRC4B (490-540 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | LRRC4B |
| Gene ID: | 94030 |
| Uniprot ID: | LRC4B_HUMAN |
| Immunogen Region: | 490-540 aa |
| Specificity: | Specific for LRRC4B. |
| Immunogen: | A synthetic peptide from aa region 490-540 of human LRRC4B conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 94% identity with rat and mouse sequences. |
| Function | Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 4bNetrin-G3 LigandNgl-3 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinPresynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 4b antibodyAnti-Netrin-G3 Ligand antibodyAnti-Ngl-3 antibodyAnti-LRRC4B antibodyAnti-LRIG4 antibody |
Information sourced from Uniprot.org