Anti-LRRC4B antibody (490-540 aa) (STJ13101328)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 490-540 of human LRRC4B conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 94% identity with rat and mouse sequences.
General Information
| Short Description | Rabbit polyclonal anti-LRRC4B (490-540 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | LRRC4B |
| Gene ID | 94030 |
| Uniprot ID | LRC4B_HUMAN |
| Immunogen | A synthetic peptide from aa region 490-540 of human LRRC4B conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 94% identity with rat and mouse sequences. |
| Immunogen Region | 490-540 aa |
| Specificity | Specific for LRRC4B. |
Additional Info
| Function | Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 4bNetrin-G3 LigandNgl-3 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinPresynaptic Cell Membrane |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 4b antibodyAnti-Netrin-G3 Ligand antibodyAnti-Ngl-3 antibodyAnti-LRRC4B antibodyAnti-LRIG4 antibody |
Information sourced from Uniprot.org