Anti-LRIT3 antibody (156-206 aa) (STJ197620)

SKU:
STJ197620
£48.00 - £252.00
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (156-206 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LRIT3
Gene ID: 345193
Uniprot ID: LRIT3_HUMAN
Immunogen Region: 156-206 aa
Specificity: This antibody detects endogenous levels of human LRIT3
Immunogen: Synthesized peptide derived from the human LRIT3 at the amino acid range 156-206
Post Translational Modifications Glycosylated.
Function Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells. Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina. Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips. Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles. May also have a role in cone synapse formation. Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi. Could be a regulator of the FGFRs.
Protein Name Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3
Cellular Localisation Cell Projection
Dendrite
Perikaryon
Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Punctate Expression At Dendrite Tips
Alternative Antibody Names Anti-Leucine-Rich Repeat - Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3 antibody
Anti-LRIT3 antibody

Information sourced from Uniprot.org

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