Western blot analysis of lysates from HL-60 cells, using LPAR2 Rabbit polyclonal antibody (STJ117019) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-LPAR2 antibody (250-350) (STJ117019)

SKU:
STJ117019
£112.50 - £524.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LPAR2
Uniprot ID: LPAR2_HUMAN
Immunogen Region: 250-350
Specificity: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LPAR2 (NP_004711.2).
Immunogen Sequence: FVVCWTPGQVVLLLDGLGCE SCNVLAVEKYFLLLAEANSL VNAAVYSCRDAEMRRTFRRL LCCACLRQSTRESVHYTSSA QGGASTRIMLPENGHPLMDS T
Tissue Specificity Expressed most abundantly in testes and peripheral blood leukocytes with less expression in pancreas, spleen, thymus and prostate. Little or no expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney, ovary, small intestine, or colon.
Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
Protein Name Lysophosphatidic Acid Receptor 2
Lpa Receptor 2
Lpa-2
Lysophosphatidic Acid Receptor Edg-4
Cellular Localisation Cell Surface
Cell Membrane
Multi-Pass Membrane Protein
Prior To Lpa Treatment Found Predominantly At The Cell Surface But In The Presence Of Lpa Colocalizes With Rala In The Endocytic Vesicles
Alternative Antibody Names Anti-Lysophosphatidic Acid Receptor 2 antibody
Anti-Lpa Receptor 2 antibody
Anti-Lpa-2 antibody
Anti-Lysophosphatidic Acid Receptor Edg-4 antibody
Anti-LPAR2 antibody
Anti-EDG4 antibody
Anti-LPA2 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ92829 Anti-LPAR2 antibody (271-320 aa) (STJ92829) Rabbit Polyclonal Human/Mouse/Monkey WB/IF/ELISA
STJ116937 Anti-GNAZ antibody (250-350) (STJ116937) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ117347 Anti-FLVCR1 antibody (250-350) (STJ117347) Rabbit Polyclonal Human WB/ELISA
STJ119668 Anti-TOM1L1 antibody (250-350) (STJ119668) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ22815 Anti-BMP4 antibody (250-350) (STJ22815) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ118818 Anti-KCNA4 antibody (250-350) (STJ118818) Rabbit Polyclonal Mouse/Rat WB/ELISA
STJ116859 Anti-PDGFD antibody (250-350) (STJ116859) Rabbit Polyclonal Human/Mouse/Rat WB/ELISA
STJ117140 Anti-SOX7 antibody (250-350) (STJ117140) Rabbit Polyclonal Mouse WB/ELISA
STJ118107 Anti-CSNK1D antibody (250-350) (STJ118107) Rabbit Polyclonal Rat WB/ELISA
!