| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Lysyl oxidase homolog 4 (39-89 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LOXL4 |
| Gene ID: | 84171 |
| Uniprot ID: | LOXL4_HUMAN |
| Immunogen Region: | 39-89 aa |
| Specificity: | This antibody detects endogenous levels of LOXL4 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human LOXL4 at the amino acid range 39-89 |
| Post Translational Modifications | The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine. May be proteolytically cleaved by BMP1. |
| Function | Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers. |
| Protein Name | Lysyl Oxidase Homolog 4Lysyl Oxidase-Like Protein 4Lysyl Oxidase-Related Protein C |
| Database Links | Reactome: R-HSA-1566948Reactome: R-HSA-2243919 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Lysyl Oxidase Homolog 4 antibodyAnti-Lysyl Oxidase-Like Protein 4 antibodyAnti-Lysyl Oxidase-Related Protein C antibodyAnti-LOXL4 antibodyAnti-LOXC antibody |
Information sourced from Uniprot.org