• Immunocytochemistry staining of Hela cells fixed with 4% Paraformaldehyde and using anti-Lamin B1 mouse mAb (dilution 1:100).
  • Western blot detection of Lamin B1 in COS7, Molt-4, A549 and 3T3 cell lysates using Lamin B1 mouse mAb (dilution 1:500).Predicted band size:68kDa.Observed band size:68kDa.

Anti-LMNB1 antibody [5G8-D3-H7] (STJ99312)

SKU:
STJ99312

£144.00 - £348.00
Current Stock:
Host: Mouse
Applications: WB
Reactivity: Human/Mouse/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Lamin-B1 is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: 5G8-D3-H7
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LMNB1
Gene ID: 4001
Uniprot ID: LMNB1_HUMAN
Specificity: This antibody detects endogenous levels of Lamin B1 and does not cross-react with related proteins.
Immunogen: Recombinant human Lamin B1 protein.
Function Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively.
Protein Name Lamin-B1
Database Links Reactome: R-HSA-1221632
Reactome: R-HSA-2559584
Reactome: R-HSA-2980766
Reactome: R-HSA-2995383
Reactome: R-HSA-352238
Reactome: R-HSA-4419969
Reactome: R-HSA-8862803
Reactome: R-HSA-8950505
Reactome: R-HSA-9013405
Reactome: R-HSA-9035034
Cellular Localisation Nucleus Lamina
Alternative Antibody Names Anti-Lamin-B1 antibody
Anti-LMNB1 antibody
Anti-LMN2 antibody
Anti-LMNB antibody

Information sourced from Uniprot.org

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