• STJ70557 staining (1µg/ml) of Mouse Heart lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-Lime1-Mouse antibody (C-Term) (STJ70557)

SKU:
STJ70557-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Lime1-Mouse (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-Recommended for use at 0.5-2µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Immunogen Region: C-Term
Accession Number: NP_076173.1
Immunogen Sequence: ENVYESIKEMGL
Post Translational Modifications Palmitoylation of Cys-28 and Cys-31 is required for raft targeting. Phosphorylated on tyrosines upon TCR activation and/or CD4 coreceptor stimulation, or upon BCR stimulation.which leads to the recruitment of SH2-containing proteins.
Function Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.
Protein Name Lck-Interacting Transmembrane Adapter 1
Lck-Interacting Molecule
Cellular Localisation Cell Membrane
Single-Pass Type Iii Membrane Protein
Present In Lipid Rafts
Recruited To The Immunological Synapse Upon Conjugation Of T-Cell With Antigen-Presenting Cell
Alternative Antibody Names Anti-Lck-Interacting Transmembrane Adapter 1 antibody
Anti-Lck-Interacting Molecule antibody
Anti-Lime1 antibody
Anti-Lime antibody

Information sourced from Uniprot.org

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