• Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-pancreas, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Western blot analysis of HepG2 cells using LIR-7 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-LILRA2 antibody (121-170 aa) (STJ96831)

SKU:
STJ96831

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Leukocyte immunoglobulin-like receptor subfamily A member 2 (121-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LILRA2
Gene ID: 11027
Uniprot ID: LIRA2_HUMAN
Immunogen Region: 121-170 aa
Specificity: LIR-7 Polyclonal Antibody detects endogenous levels of LIR-7 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA2 at the amino acid range 121-170
Function Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils. In monocytes, activation leads to the release of CSF2, CF3, IL6, CXCL8 and CCL3 and down-regulates responses to bacterial lipopolysaccharide (LPS), possibly via down-regulation of TLR4 expression and reduced signaling via TLR4. In eosinophils, activation by ligand binding leads to the release of RNASE2, IL4 and leukotriene C4. Does not bind class I MHC antigens.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2
Cd85 Antigen-Like Family Member H
Immunoglobulin-Like Transcript 1
Ilt-1
Leukocyte Immunoglobulin-Like Receptor 7
Lir-7
Cd Antigen Cd85h
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 4: Secreted
Alternative Antibody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2 antibody
Anti-Cd85 Antigen-Like Family Member H antibody
Anti-Immunoglobulin-Like Transcript 1 antibody
Anti-Ilt-1 antibody
Anti-Leukocyte Immunoglobulin-Like Receptor 7 antibody
Anti-Lir-7 antibody
Anti-Cd Antigen Cd85h antibody
Anti-LILRA2 antibody
Anti-ILT1 antibody
Anti-LIR7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance