Anti-LEFTY1 antibody (77-366) (STJ117584)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LEFTY1 (77-366) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LEFTY1 |
| Gene ID | 10637 |
| Uniprot ID | LFTY1_HUMAN |
| Immunogen Region | 77-366 |
| Immunogen Sequence | RFSQSFREVAGRFLALEAST HLLVFGMEQRLPPNSELVQA VLRLFQEPVPKAALHRHGRL SPRSARARVTVEWLRVRDDG SNRTSLIDSRLVSVHESGWK AFDVTEAVNFWQQLSRPRQP LLLQVSVQREHLGPLASGAH KLVRFASQGAPAGLGEPQLE LHTLDLGDYGAQGDCDPEAP MTEGTRCCRQEMYIDLQGMK WAENWVLEPPGFLAYECVGT CRQPPEALAFKWPFLGPRQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 77-366 of human LEFTY1 (NP_066277.1). |
Additional Info
| Post Translational Modifications | The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner. |
| Function | Required for left-right axis determination as a regulator of LEFTY2 and NODAL. |
| Protein Name | Left-Right Determination Factor 1Left-Right Determination Factor BProtein Lefty-1Protein Lefty-B |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Left-Right Determination Factor 1 antibodyAnti-Left-Right Determination Factor B antibodyAnti-Protein Lefty-1 antibodyAnti-Protein Lefty-B antibodyAnti-LEFTY1 antibodyAnti-LEFTB antibodyAnti-LEFTYB antibodyAnti-UNQ278 antibodyAnti-PRO317 antibody |
Information sourced from Uniprot.org