Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-LBP (250-350) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LBP |
Gene ID: |
3929 |
Uniprot ID: |
LBP_HUMAN |
Immunogen Region: |
250-350 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LBP (NP_004130.2). |
Immunogen Sequence: |
EIFHRNHRSPVTLLAAVMSL PEEHNKMVYFAISDYVFNTA SLVYHEEGYLNFSITDDMIP PDSNIRLTTKSFRPFVPRLA RLYPNMNLELQGSVPSAPLL N |
Tissue Specificity | Detected in blood serum (at protein level). |
Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. |
Protein Name | Lipopolysaccharide-Binding ProteinLbp |
Database Links | Reactome: R-HSA-166016Reactome: R-HSA-166020Reactome: R-HSA-5686938Reactome: R-HSA-6785807 |
Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
Alternative Antibody Names | Anti-Lipopolysaccharide-Binding Protein antibodyAnti-Lbp antibodyAnti-LBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance