• Immunohistochemistry of baboon lung with Anti-LAT2 primary antibody (STJ501582) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-LAT2 antibody (40-90) (STJ501582)

SKU:
STJ501582-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LAT2 (40-90) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.54-0.72 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: LAT2
Gene ID: 7462
Uniprot ID: NTAL_HUMAN
Immunogen Region: 40-90
Immunogen: Synthetic peptide taken within amino acid region 40-90 on LAT2 protein.
Tissue Specificity Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level).
Post Translational Modifications Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells.which induces the recruitment of GRB2. May be polyubiquitinated.
Function Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Protein Name Linker For Activation Of T-Cells Family Member 2
Linker For Activation Of B-Cells
Membrane-Associated Adapter Molecule
Non-T-Cell Activation Linker
Williams-Beuren Syndrome Chromosomal Region 15 Protein
Williams-Beuren Syndrome Chromosomal Region 5 Protein
Database Links Reactome: R-HSA-2730905
Cellular Localisation Cell Membrane
Single-Pass Type Iii Membrane Protein
Present In Lipid Rafts
Alternative Antibody Names Anti-Linker For Activation Of T-Cells Family Member 2 antibody
Anti-Linker For Activation Of B-Cells antibody
Anti-Membrane-Associated Adapter Molecule antibody
Anti-Non-T-Cell Activation Linker antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 15 Protein antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 5 Protein antibody
Anti-LAT2 antibody
Anti-LAB antibody
Anti-NTAL antibody
Anti-WBS15 antibody
Anti-WBSCR15 antibody
Anti-WBSCR5 antibody
Anti-HSPC046 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance