| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LARP6 |
| Gene ID: | 55323 |
| Uniprot ID: | LARP6_HUMAN |
| Immunogen Region: | 1-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human LARP6 (NP_060827.2). |
| Immunogen Sequence: | MAQSGGEARPGPKTAVQIRV AIQEAEDVDELEDEEEGAET RGAGDPARYLSPGWGSASEE EPSRGHSGTTASGGENERED LEQEWKPPDEELIKKLVDQI EFYFSDENLEKDAFLLKHVR RNKLGYVSVKLLTSFKKVKH LTRDWRTTAHALKYSVVLEL NEDHRKVRRTTPVPLFPNEN LPSKMLLVYDLYLSPKLWAL ATPQKNGRVQEKVMEHLLKL FGTFGVISSVRILKPGREL |
| Tissue Specificity | Expressed in numerous tissues. |
| Function | Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. |
| Protein Name | La-Related Protein 6AcheronAchnLa Ribonucleoprotein Domain Family Member 6 |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-La-Related Protein 6 antibodyAnti-Acheron antibodyAnti-Achn antibodyAnti-La Ribonucleoprotein Domain Family Member 6 antibodyAnti-LARP6 antibody |
Information sourced from Uniprot.org
