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Anti-laminin Alpha 4 antibody [3H2] (STJA0002806)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenImmunoaffinity-purified Laminin 411 (laminin-8 ( Alpha 4 Beta 1 Gamma 1) from platelets. Human laminin a4
General Information
| Short Description | Mouse monoclonal anti-Laminin Alpha 4 for use in ELISA, IHC, WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC/WB/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3H2 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Protein G purification |
| Dilution Range | ELISA titer 0.02 ยตg/ml; WB, reduced conditions; 0.5 to 1 ยตg/ml; IP 0.5 mg/ml; IHC dilution 5 to 10 ยตg/ml Monoclonal antibody working titer has to be established practically for each particular antigen and assay format |
| Formulation | PBS pH 7.4, with 0.1% sodium azide |
| Storage Instruction | Store at-20 to-70 ยฐC upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles |
Target Information
| Gene Symbol | LAMA4 |
| Gene ID | 3910 |
| Uniprot ID | LAMA4_HUMAN |
| Immunogen | Immunoaffinity-purified Laminin 411 (laminin-8 ( Alpha 4 Beta 1 Gamma 1) from platelets. Human laminin a4 |
| Specificity | Human laminin Alpha 4 |
Additional Info
| Tissue Specificity | Detected in placenta (at protein level). Detected in fibroblasts and urine (at protein level). In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver.weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Alpha-4Laminin-14 Subunit AlphaLaminin-8 Subunit AlphaLaminin-9 Subunit Alpha |
| Database Links | Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Basement Membrane Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-4 antibodyAnti-Laminin-14 Subunit Alpha antibodyAnti-Laminin-8 Subunit Alpha antibodyAnti-Laminin-9 Subunit Alpha antibodyAnti-LAMA4 antibody |
Information sourced from Uniprot.org