| Host: |
Mouse |
| Applications: |
ELISA/IHC/WB/IP |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Laminin Alpha 4 is suitable for use in ELISA, Immunohistochemistry, Western Blot and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
3H2 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
PBS pH 7.4, with 0.1% sodium azide |
| Purification: |
Protein G purification |
| Dilution Range: |
ELISA titer 0.02 µg/ml; WB, reduced conditions; 0.5 to 1 µg/ml; IP 0.5 mg/ml; IHC dilution 5 to 10 µg/ml Monoclonal antibody working titer has to be established practically for each particular antigen and assay format |
| Storage Instruction: |
Store at-20 to-70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles |
| Gene Symbol: |
LAMA4 |
| Gene ID: |
3910 |
| Uniprot ID: |
LAMA4_HUMAN |
| Specificity: |
Human laminin Alpha 4 |
| Immunogen: |
Immunoaffinity-purified Laminin 411 (laminin-8 ( Alpha 4 Beta 1 Gamma 1) from platelets. Human laminin a4 |
| Tissue Specificity | Detected in placenta (at protein level). Detected in fibroblasts and urine (at protein level). In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver.weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Protein Name | Laminin Subunit Alpha-4Laminin-14 Subunit AlphaLaminin-8 Subunit AlphaLaminin-9 Subunit Alpha |
| Database Links | Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Basement Membrane Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-4 antibodyAnti-Laminin-14 Subunit Alpha antibodyAnti-Laminin-8 Subunit Alpha antibodyAnti-Laminin-9 Subunit Alpha antibodyAnti-LAMA4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
