| Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2Cell-Scattering Factor 140 Kda SubunitCsf 140 Kda SubunitEpiligrin Subunit GammaKalinin Subunit GammaKalinin/Nicein/Epiligrin 100 Kda SubunitLadsin 140 Kda SubunitLaminin B2t ChainLaminin-5 Subunit GammaLarge Adhesive Scatter Factor 140 Kda SubunitNicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Gamma-2 antibodyAnti-Cell-Scattering Factor 140 Kda Subunit antibodyAnti-Csf 140 Kda Subunit antibodyAnti-Epiligrin Subunit Gamma antibodyAnti-Kalinin Subunit Gamma antibodyAnti-Kalinin/Nicein/Epiligrin 100 Kda Subunit antibodyAnti-Ladsin 140 Kda Subunit antibodyAnti-Laminin B2t Chain antibodyAnti-Laminin-5 Subunit Gamma antibodyAnti-Large Adhesive Scatter Factor 140 Kda Subunit antibodyAnti-Nicein Subunit Gamma antibodyAnti-LAMC2 antibodyAnti-LAMB2T antibodyAnti-LAMNB2 antibody |
Information sourced from Uniprot.org
