| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-LAMA5 (1029-1043) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Not yet tested-our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 400kDa according to NP_005551.3. Therefore we cannot |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | LAMA5 |
| Gene ID: | 3911 |
| Uniprot ID: | LAMA5_HUMAN |
| Immunogen Region: | 1029-1043 |
| Accession Number: | NP_005551.3 |
| Immunogen Sequence: | EACTYRPSAQQSGDN |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2. |
| Protein Name | Laminin Subunit Alpha-5Laminin-10 Subunit AlphaLaminin-11 Subunit AlphaLaminin-15 Subunit Alpha |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-8874081 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Names | Anti-Laminin Subunit Alpha-5 antibodyAnti-Laminin-10 Subunit Alpha antibodyAnti-Laminin-11 Subunit Alpha antibodyAnti-Laminin-15 Subunit Alpha antibodyAnti-LAMA5 antibodyAnti-KIAA0533 antibodyAnti-KIAA1907 antibody |
Information sourced from Uniprot.org
