Anti-L1RE1 antibody (157-330 aa) [R01-0H7] (STJA0012449)

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STJA0012449-100
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Host: Rabbit
Applications: WB/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-LINE 1 ORF1p (157-330 aa) is suitable for use in Western Blot and Immunoprecipitation research applications.
Clonality : Monoclonal
Clone ID : R01-0H7
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/ml
Dilution Range: WB 1:500-1:1000
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: L1RE1
Uniprot ID: LORF1_HUMAN
Immunogen Region: 157-330 aa
Immunogen: Recombinant protein of human LINE-1 ORF1p
Post Translational Modifications Polyubiquitinated, probably by UBR2, which induces its degradation.
Function Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.
Protein Name Line-1 Retrotransposable Element Orf1 Protein
L1orf1p
Line Retrotransposable Element 1
Line1 Retrotransposable Element 1
Cellular Localisation Nucleus
Nucleolus
Cytoplasm
Cytoplasmic Ribonucleoprotein Granule
Stress Granule
Colocalizes With Its Encoding Rna In Cytoplasmic Ribonucleoprotein Particle
Mainly Cytoplasmic
Rarely Detected In The Nucleus
Possibly Within The Nucleolus
Alternative Antibody Names Anti-Line-1 Retrotransposable Element Orf1 Protein antibody
Anti-L1orf1p antibody
Anti-Line Retrotransposable Element 1 antibody
Anti-Line1 Retrotransposable Element 1 antibody
Anti-L1RE1 antibody
Anti-LRE1 antibody

Information sourced from Uniprot.org