Post Translational Modifications | Polyubiquitinated, probably by UBR2, which induces its degradation. |
Function | Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded. |
Protein Name | Line-1 Retrotransposable Element Orf1 ProteinL1orf1pLine Retrotransposable Element 1Line1 Retrotransposable Element 1 |
Cellular Localisation | NucleusNucleolusCytoplasmCytoplasmic Ribonucleoprotein GranuleStress GranuleColocalizes With Its Encoding Rna In Cytoplasmic Ribonucleoprotein ParticleMainly CytoplasmicRarely Detected In The NucleusPossibly Within The Nucleolus |
Alternative Antibody Names | Anti-Line-1 Retrotransposable Element Orf1 Protein antibodyAnti-L1orf1p antibodyAnti-Line Retrotransposable Element 1 antibodyAnti-Line1 Retrotransposable Element 1 antibodyAnti-L1RE1 antibodyAnti-LRE1 antibody |
Information sourced from Uniprot.org