Anti-KYAT3 antibody (295-394) (STJ11105627)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Kynurenine--Oxoglutarate Transaminase 3 (295-394) antibody for use in IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KYAT3 |
| Gene ID | 56267 |
| Uniprot ID | KAT3_HUMAN |
| Immunogen Region | 295-394 |
| Immunogen Sequence | PNHLIKHLQTVQQNTIYTCA TPLQEALAQAFWIDIKRMDD PECYFNSLPKELEVKRDRMV RLLESVGLKPIVPDGGYFII ADVSLLDPDLSDMKNNEPYD |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 295-394 of human KYAT3 (NP_001008661.1). |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro). |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 3Cysteine-S-Conjugate Beta-Lyase 2Kynurenine Aminotransferase 3Kynurenine Aminotransferase IiiKatiiiKynurenine--Glyoxylate TransaminaseKynurenine--Oxoglutarate Transaminase Iii |
| Database Links | Reactome: R-HSA-71240 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kynurenine--Oxoglutarate Transaminase 3 antibodyAnti-Cysteine-S-Conjugate Beta-Lyase 2 antibodyAnti-Kynurenine Aminotransferase 3 antibodyAnti-Kynurenine Aminotransferase Iii antibodyAnti-Katiii antibodyAnti-Kynurenine--Glyoxylate Transaminase antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iii antibodyAnti-KYAT3 antibodyAnti-CCBL2 antibodyAnti-KAT3 antibody |
Information sourced from Uniprot.org