| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro). |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 3Cysteine-S-Conjugate Beta-Lyase 2Kynurenine Aminotransferase 3Kynurenine Aminotransferase IiiKatiiiKynurenine--Glyoxylate TransaminaseKynurenine--Oxoglutarate Transaminase Iii |
| Database Links | Reactome: R-HSA-71240 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kynurenine--Oxoglutarate Transaminase 3 antibodyAnti-Cysteine-S-Conjugate Beta-Lyase 2 antibodyAnti-Kynurenine Aminotransferase 3 antibodyAnti-Kynurenine Aminotransferase Iii antibodyAnti-Katiii antibodyAnti-Kynurenine--Glyoxylate Transaminase antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iii antibodyAnti-KYAT3 antibodyAnti-CCBL2 antibodyAnti-KAT3 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of NIH-3T3 cells using [KO Validated] Fascin/Fascin/FSCN1 Rabbit polyclonal antibody (STJ23712) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99661/384925/STJ23712_1__28840.1713153730.jpg?c=1 "Immunofluorescence analysis of NIH-3T3 cells using [KO Validated] Fascin/Fascin/FSCN1 Rabbit polyclonal antibody (STJ23712) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.")
