| Host: |
Rabbit |
| Applications: |
IHC-P/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
IHC-P:1:50-1:200IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KYAT3 |
| Gene ID: |
56267 |
| Uniprot ID: |
KAT3_HUMAN |
| Immunogen Region: |
295-394 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 295-394 of human KYAT3 (NP_001008661.1). |
| Immunogen Sequence: |
PNHLIKHLQTVQQNTIYTCA TPLQEALAQAFWIDIKRMDD PECYFNSLPKELEVKRDRMV RLLESVGLKPIVPDGGYFII ADVSLLDPDLSDMKNNEPYD |
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro). |
| Protein Name | Kynurenine--Oxoglutarate Transaminase 3Cysteine-S-Conjugate Beta-Lyase 2Kynurenine Aminotransferase 3Kynurenine Aminotransferase IiiKatiiiKynurenine--Glyoxylate TransaminaseKynurenine--Oxoglutarate Transaminase Iii |
| Database Links | Reactome: R-HSA-71240 |
| Alternative Antibody Names | Anti-Kynurenine--Oxoglutarate Transaminase 3 antibodyAnti-Cysteine-S-Conjugate Beta-Lyase 2 antibodyAnti-Kynurenine Aminotransferase 3 antibodyAnti-Kynurenine Aminotransferase Iii antibodyAnti-Katiii antibodyAnti-Kynurenine--Glyoxylate Transaminase antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iii antibodyAnti-KYAT3 antibodyAnti-CCBL2 antibodyAnti-KAT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
