Anti-KRT73 antibody (STJA0004564)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFull length fusion protein
General Information
| Short Description | Rabbit polyclonal anti-Keratin-Type Ii Cytoskeletal 73 for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:40-1:200 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT73 |
| Gene ID | 319101 |
| Uniprot ID | K2C73_HUMAN |
| Immunogen | Full length fusion protein |
Additional Info
| Tissue Specificity | Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level). |
| Function | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). |
| Protein Name | Keratin - Type Ii Cytoskeletal 73Cytokeratin-73Ck-73Keratin-73K73Type Ii Inner Root Sheath-Specific Keratin-K6irs3Type-Ii Keratin Kb36 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 73 antibodyAnti-Cytokeratin-73 antibodyAnti-Ck-73 antibodyAnti-Keratin-73 antibodyAnti-K73 antibodyAnti-Type Ii Inner Root Sheath-Specific Keratin-K6irs3 antibodyAnti-Type-Ii Keratin Kb36 antibodyAnti-KRT73 antibodyAnti-K6IRS3 antibodyAnti-KB36 antibodyAnti-KRT6IRS3 antibody |
Information sourced from Uniprot.org