| Short Description : | Mouse monoclonal anti-Keratin, type II cytoskeletal 7 for use in IF, WB, IHC and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/WB/IHC/IP |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 12D7 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IF 1:50-200WB 1:1000-2000IHC 1:200IP 1:200 |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT7 |
| Gene ID: | 3855 |
| Uniprot ID: | K2C7_HUMAN |
| Immunogen: | Synthetic Peptide of CK7 |
| Specificity: | The antibody detects endogenous CK7 proteins. |
| Post Translational Modifications | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
| Protein Name | Keratin - Type Ii Cytoskeletal 7Cytokeratin-7Ck-7Keratin-7K7SarcolectinType-Ii Keratin Kb7 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 7 antibodyAnti-Cytokeratin-7 antibodyAnti-Ck-7 antibodyAnti-Keratin-7 antibodyAnti-K7 antibodyAnti-Sarcolectin antibodyAnti-Type-Ii Keratin Kb7 antibodyAnti-KRT7 antibodyAnti-SCL antibody |
Information sourced from Uniprot.org
