• Immunohistochemistry analysis of paraffin-embedded mouse kidney using KLHL42 antibody (STJ116406) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded mouse testis leydig using KLHL42 antibody (STJ116406) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human gastric cancer using KLHL42 antibody (STJ116406) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human liver using KLHL42 antibody (STJ116406) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-KLHL42 antibody (206-505) (STJ116406)

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STJ116406

£112.50 - £522.50
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Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KLHL42 (206-505) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KLHL42
Gene ID: 57542
Uniprot ID: KLH42_HUMAN
Immunogen Region: 206-505
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human KLHL42 (NP_065833.1).
Immunogen Sequence: PLAPHPYQGEPPSMLRYEEM TERWFPLANNLPPDLVNVRG YGSAILDNYLFIVGGYRITS QEISAAHSYNPSTNEWLQVA SMNQKRSNFKLVAVNSKLYA IGGQAVSNVECYNPEQDAWN FVAPLPNPLAEFSACECKGK IYVIGGYTTRDRNMNILQYC PSSDMWTLFETCDVHIRKQQ MVSVEETIYIVGGCLHELGP NRRSSQSEDMLTVQSYNTVT RQWLYLKENTSKSGLNLTC
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
Protein Name Kelch-Like Protein 42
Cullin-3-Binding Protein 9
Ctb9
Kelch Domain-Containing Protein 5
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Predominantly In Mitotic Cells
Localized Diffusely In The Cytoplasm During The Interphase
During Metaphase Is Localized Throughout The Cell And More Widely Dispersed Than The Microtubules
In Anaphase Cells Is Localized Between The Two Sets Of Separated Chromosomes As Well As At The Spindle Poles
During Telophase Is Localized Arround The Nuclei Of The Two Daughter Cells
Not Detected At The Midbody Region During Cytokinesis
Alternative Antibody Names Anti-Kelch-Like Protein 42 antibody
Anti-Cullin-3-Binding Protein 9 antibody
Anti-Ctb9 antibody
Anti-Kelch Domain-Containing Protein 5 antibody
Anti-KLHL42 antibody
Anti-KIAA1340 antibody
Anti-KLHDC5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance