| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Krueppel-like factor 11 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF11 |
| Gene ID: | 8462 |
| Uniprot ID: | KLF11_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | TIEG2 Polyclonal Antibody detects endogenous levels of TIEG2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human KLF11 at the amino acid range 1-50 |
| Function | Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. |
| Protein Name | Krueppel-Like Factor 11Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2Tgfb-Inducible Early Growth Response Protein 2Tieg-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 11 antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 2 antibodyAnti-Tieg-2 antibodyAnti-KLF11 antibodyAnti-FKLF antibodyAnti-TIEG2 antibody |
Information sourced from Uniprot.org