| Post Translational Modifications | Ubiquitinated.mediated by SIAH1 and leading to its subsequent proteasomal degradation. |
| Function | Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock.binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation. |
| Protein Name | Krueppel-Like Factor 10Egr-AlphaTransforming Growth Factor-Beta-Inducible Early Growth Response Protein 1Tgfb-Inducible Early Growth Response Protein 1Tieg-1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 10 antibodyAnti-Egr-Alpha antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 1 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 1 antibodyAnti-Tieg-1 antibodyAnti-KLF10 antibodyAnti-TIEG antibodyAnti-TIEG1 antibody |
Information sourced from Uniprot.org
