| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIR3DL3 |
| Uniprot ID: | KI3L3_HUMAN |
| Immunogen Region: | 26-322 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-322 of human KIR3DL3 (NP_703144.3). |
| Immunogen Sequence: | QDKPFLSAWPGTVVSEGQHV TLQCRSRLGFNEFSLSKEDG MPVPELYNRIFRNSFLMGPV TPAHAGTYRCCSSHPHSPTG WSAPSNPVVIMVTGVHRKPS LLAHPGPLVKSGETVILQCW SDVRFERFLLHREGITEDPL RLVGQLHDAGSQVNYSMGPM TPALAGTYRCFGSVTHLPYE LSAPSDPLDIVVVGLYGKPS LSAQPGPTVQAGENVTLSCS SRSLFDIYHLSREAEAGEL |
| Function | Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl3Cd158 Antigen-Like Family Member ZKiller Cell Inhibitory Receptor 1Cd Antigen Cd158z |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl3 antibodyAnti-Cd158 Antigen-Like Family Member Z antibodyAnti-Killer Cell Inhibitory Receptor 1 antibodyAnti-Cd Antigen Cd158z antibodyAnti-KIR3DL3 antibodyAnti-CD158Z antibodyAnti-KIR3DL7 antibodyAnti-KIRC1 antibody |
Information sourced from Uniprot.org