| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Killer cell immunoglobulin-like receptor 3DL2 (221-270 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIR3DL2 |
| Gene ID: | 3812 |
| Uniprot ID: | KI3L2_HUMAN |
| Immunogen Region: | 221-270 aa |
| Specificity: | The antibody detects endogenous CD158k |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 221-270 |
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl2 antibodyAnti-Cd158 Antigen-Like Family Member K antibodyAnti-Natural Killer-Associated Transcript 4 antibodyAnti-Nkat-4 antibodyAnti-P70 Natural Killer Cell Receptor Clone Cl-5 antibodyAnti-P70 Nk Receptor Cl-5 antibodyAnti-Cd Antigen Cd158k antibodyAnti-KIR3DL2 antibodyAnti-CD158K antibodyAnti-NKAT4 antibody |
Information sourced from Uniprot.org