| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S1MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLC1 |
| Gene ID: | 3831 |
| Uniprot ID: | KLC1_HUMAN |
| Immunogen Region: | 450-550 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866). |
| Immunogen Sequence: | GGWYKACKVDSPTVTTTLKN LGALYRRQGKFEAAETLEEA AMRSRKQGLDNVHKQRVAEV LNDPENMEKRRSRESLNVDV VKYESGPDGGEEVSMSVEWN G |
| Tissue Specificity | Found in a variety of tissues. Mostly abundant in brain and spine. |
| Post Translational Modifications | Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles. |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| Protein Name | Kinesin Light Chain 1Klc 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-9725370Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionGrowth ConeCytoplasmic VesicleCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Kinesin Light Chain 1 antibodyAnti-Klc 1 antibodyAnti-KLC1 antibodyAnti-KLC antibodyAnti-KNS2 antibody |
Information sourced from Uniprot.org