• Western blot analysis of extracts of Mouse brain, using Kinesin light chain 1 (Kinesin light chain 1 (KLC1) ) antibody (STJ11102981) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
  • Western blot analysis of extracts of various cell lines, using Kinesin light chain 1 (Kinesin light chain 1 (KLC1) ) antibody (STJ11102981) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-Kinesin light chain 1 antibody (450-550) [S1MR] (STJ11102981)

SKU:
STJ11102981

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Kinesin light chain 1 (KLC1) (450-550) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KLC1
Gene ID: 3831
Uniprot ID: KLC1_HUMAN
Immunogen Region: 450-550
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866).
Immunogen Sequence: GGWYKACKVDSPTVTTTLKN LGALYRRQGKFEAAETLEEA AMRSRKQGLDNVHKQRVAEV LNDPENMEKRRSRESLNVDV VKYESGPDGGEEVSMSVEWN G
Tissue Specificity Found in a variety of tissues. Mostly abundant in brain and spine.
Post Translational Modifications Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles.
Function Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Protein Name Kinesin Light Chain 1
Klc 1
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-5625970
Reactome: R-HSA-6811434
Reactome: R-HSA-9725370
Reactome: R-HSA-983189
Cellular Localisation Cell Projection
Growth Cone
Cytoplasmic Vesicle
Cytoplasm
Cytoskeleton
Alternative Antibody Names Anti-Kinesin Light Chain 1 antibody
Anti-Klc 1 antibody
Anti-KLC1 antibody
Anti-KLC antibody
Anti-KNS2 antibody

Information sourced from Uniprot.org

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