• Western blot analysis of extracts of various cell lines, using KIF23 rabbit monoclonal antibody (STJ11102187) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Immunoprecipitation analysis of 300 Mu g extracts of HeLa cells using 3 Mu g KIF23 antibody (STJ11102187). Western blot was performed from the immunoprecipitate using KIF23 antibody (STJ11102187) at a dilution of 1:1000.

Anti-KIF23 antibody (801-960) [S7MR] (STJ11102187)

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STJ11102187

£146.50 - £639.50
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Host: Rabbit
Applications: WB/IP
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-KIF23 (801-960) is suitable for use in Western Blot and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IP 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIF23
Gene ID: 9493
Uniprot ID: KIF23_HUMAN
Immunogen Region: 801-960
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 801-960 of human KIF23 (Q02241).
Immunogen Sequence: NAPPIRLRHRRSRSAGDRWV DHKPASNMQTETVMQPHVPH AITVSVANEKALAKCEKYML THQELASDGEIETKLIKGDI YKTRGGGQSVQFTDIETLKQ ESPNGSRKRRSSTVAPAQPD GAESEWTDVETRCSVAVEMR AGSQLGPGYQHHAQPKRKKP
Tissue Specificity Widely expressed.
Post Translational Modifications Ubiquitinated. Deubiquitinated by USP8/UBPY.
Function Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
Protein Name Kinesin-Like Protein Kif23
Kinesin-Like Protein 5
Mitotic Kinesin-Like Protein 1
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-6811434
Reactome: R-HSA-68884
Reactome: R-HSA-983189
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Spindle
Midbody
Midbody Ring
Localizes To The Interzone Of Mitotic Spindles
Detected At The Midbody During Later Stages Of Mitotic Cytokinesis
Alternative Antibody Names Anti-Kinesin-Like Protein Kif23 antibody
Anti-Kinesin-Like Protein 5 antibody
Anti-Mitotic Kinesin-Like Protein 1 antibody
Anti-KIF23 antibody
Anti-KNSL5 antibody
Anti-MKLP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance