Anti-KIF22 antibody (456-665) (STJ117480)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KIF22 (456-665) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIF22 |
| Gene ID | 3835 |
| Uniprot ID | KIF22_HUMAN |
| Immunogen Region | 456-665 |
| Immunogen Sequence | QGAPLLSTPKRERMVLMKTV EEKDLEIERLKTKQKELEAK MLAQKAEEKENHCPTMLRPL SHRTVTGAKPLKKAVVMPLQ LIQEQAASPNAEIHILKNKG RKRKLESLDALEPEEKAEDC WELQISPELLAHGRQKILDL LNEGSARDLRSLQRIGPKKA QLIVGWRELHGPFSQVEDLE RVEGITGKQMESFLKANILG LAAGQRCGAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 456-665 of human KIF22 (NP_015556.1). |
Additional Info
| Tissue Specificity | Expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes. |
| Post Translational Modifications | Ubiquitinated.mediated by SIAH1 and leading to its subsequent proteasomal degradation. |
| Function | Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. |
| Protein Name | Kinesin-Like Protein Kif22Kinesin-Like Dna-Binding ProteinKinesin-Like Protein 4 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | NucleusCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif22 antibodyAnti-Kinesin-Like Dna-Binding Protein antibodyAnti-Kinesin-Like Protein 4 antibodyAnti-KIF22 antibodyAnti-KID antibodyAnti-KNSL4 antibody |
Information sourced from Uniprot.org