Function | Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria. |
Protein Name | Kinesin-Like Protein Kif1bKlp |
Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
Cellular Localisation | CytoplasmCytoskeletonHas A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With MicrotubulesIsoform 2: Cytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneAssociates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal MicrotubulesIsoform 3: MitochondrionAssociates With Mitochondria And Mediates Their Movement Along Microtubules |
Alternative Antibody Names | Anti-Kinesin-Like Protein Kif1b antibodyAnti-Klp antibodyAnti-KIF1B antibodyAnti-KIAA0591 antibodyAnti-KIAA1448 antibody |
Information sourced from Uniprot.org