• Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-KIF1B antibody (1331-1381 aa) (STJ194561)

SKU:
STJ194561

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Kinesin-like protein KIF1B (1331-1381 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIF1B
Gene ID: 23095
Uniprot ID: KIF1B_HUMAN
Immunogen Region: 1331-1381 aa
Specificity: This antibody detects endogenous levels of KIF1B at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human KIF1B at the amino acid range 1331-1381
Function Has a plus-end-directed microtubule motor activity and functions as a motor for transport of vesicles and organelles along microtubules. Isoform 2: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde synaptic vesicle transport along axonal microtubules from the cell body to the presynapse in neuronal cells. Functions as a downstream effector in a developmental apoptotic pathway that is activated when nerve growth factor (NGF) becomes limiting for neuronal progenitor cells. Isoform 3: Has a plus-end-directed microtubule motor activity and functions as a motor for anterograde transport of mitochondria.
Protein Name Kinesin-Like Protein Kif1b
Klp
Database Links Reactome: R-HSA-6811434
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Has A Plus-End-Directed Microtubule Motor Activity And Therefore Associates With Microtubules
Isoform 2: Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Associates With Synaptic Vesicles And Mediates Their Anterograde Transport Along Axonal Microtubules
Isoform 3: Mitochondrion
Associates With Mitochondria And Mediates Their Movement Along Microtubules
Alternative Antibody Names Anti-Kinesin-Like Protein Kif1b antibody
Anti-Klp antibody
Anti-KIF1B antibody
Anti-KIAA0591 antibody
Anti-KIAA1448 antibody

Information sourced from Uniprot.org

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