| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
KIF1A |
| Gene ID: |
547 |
| Uniprot ID: |
KIF1A_HUMAN |
| Immunogen Region: |
1596-1690 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1596-1690 of human KIF1A (NP_004312.2). |
| Immunogen Sequence: |
FVVVRRPYAYMYNSDKDTVE RFVLNLATAQVEYSEDQQAM LKTPNTFAVCTEHRGILLQA ASDKDMHDWLYAFNPLLAGT IRSKLSRRRSAQMRV |
| Tissue Specificity | Expressed in neurons. |
| Function | Motor for anterograde axonal transport of synaptic vesicle precursors. Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites. |
| Protein Name | Kinesin-Like Protein Kif1aAxonal Transporter Of Synaptic VesiclesMicrotubule-Based Motor Kif1aUnc-104- And Kif1a-Related ProteinHunc-104 |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionNeuron ProjectionAxonPerinuclear RegionSynapseCytoplasmic VesicleSecretory VesicleNeuronal Dense Core Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideWithin Neuronal Cells Concentrated In The AxonWith Smaller Amounts In The Perinuclear And Synaptic RegionsAccumulates At The Distal Tip Of Growing Neurites |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif1a antibodyAnti-Axonal Transporter Of Synaptic Vesicles antibodyAnti-Microtubule-Based Motor Kif1a antibodyAnti-Unc-104- And Kif1a-Related Protein antibodyAnti-Hunc-104 antibodyAnti-KIF1A antibodyAnti-ATSV antibodyAnti-C2orf20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
