Anti-Keratin 18 antibody [C-04] (STJ16101024)

Anti-Keratin 18 antibody [C-04] (STJ16101024)

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STJ16101024
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Cat/Cow/Dog/Ferret/Goat/Hamster/Horse/Human/Marmoset/Mouse/Pig/Rat/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Keratin 18 is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : C-04
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow Cytometry (1-2 µg/million cells in 0, 1 ml, fix cells in 4% PFA for 10 min, at 4°C, permeabilize with 0, 2% saponin or digitonin for 15 min, at 4°C). Immunoblotting (1-2 µg/ml). Immunofluorescence (0.5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: KRTAP10-11
Gene ID: 386678
Uniprot ID: KR10B_HUMAN
Immunogen: A hybrid (BALB/c x B6) mouse was immunized with a cytoskeleton preparation of human A431 carcinoma cell line. Fusion partner: Sp2/0.
Tissue Specificity Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root.not detected in any other tissues.
Function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Protein Name Keratin-Associated Protein 10-11
High Sulfur Keratin-Associated Protein 10.11
Keratin-Associated Protein 10.11
Keratin-Associated Protein 18-11
Keratin-Associated Protein 18.11
Database Links Reactome: R-HSA-6805567
Alternative Antibody Names Anti-Keratin-Associated Protein 10-11 antibody
Anti-High Sulfur Keratin-Associated Protein 10.11 antibody
Anti-Keratin-Associated Protein 10.11 antibody
Anti-Keratin-Associated Protein 18-11 antibody
Anti-Keratin-Associated Protein 18.11 antibody
Anti-KRTAP10-11 antibody
Anti-KAP10.11 antibody
Anti-KAP18-11 antibody
Anti-KRTAP10.11 antibody
Anti-KRTAP18-11 antibody
Anti-KRTAP18.11 antibody

Information sourced from Uniprot.org

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