| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Potassium channel subfamily T member 1 (1019-1068 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KCNT1 |
| Gene ID: | 57582 |
| Uniprot ID: | KCNT1_HUMAN |
| Immunogen Region: | 1019-1068 aa |
| Specificity: | KCNT1 Polyclonal Antibody detects endogenous levels of KCNT1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human KCNT1 at the amino acid range 1019-1068 |
| Post Translational Modifications | Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. |
| Function | Sodium-activated K(+) channel. Acts as an important mediator of neuronal membrane excitability. Contributes to the delayed outward currents. Regulates neuronal bursting in sensory neurons. Contributes to synaptic development and plasticity. |
| Protein Name | Potassium Channel Subfamily T Member 1Kca4.1Kna1.1Sodium And Chloride-Activated Atp-Sensitive Potassium Channel Slo2.2 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily T Member 1 antibodyAnti-Kca4.1 antibodyAnti-Kna1.1 antibodyAnti-Sodium And Chloride-Activated Atp-Sensitive Potassium Channel Slo2.2 antibodyAnti-KCNT1 antibodyAnti-KIAA1422 antibodyAnti-SLACK antibodyAnti-Slo2.2 antibody |
Information sourced from Uniprot.org
