• Western blot analysis of extracts of various cell lines, using KCNS3 antibody (STJ110215) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Immunohistochemistry analysis of paraffin-embedded mouse spleen using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry of paraffin-embedded rat ovary using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens).
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry of paraffin-embedded human colon carcinoma using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens).
  • Immunohistochemistry analysis of paraffin-embedded rat ovary using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry of paraffin-embedded mouse spleen using KCNS3 antibody (STJ110215) at dilution of 1:100 (40x lens).
  • Western blot analysis of extracts of various cell lines, using KCNS3 antibody (STJ110215) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-KCNS3 antibody (1-180) (STJ110215)

SKU:
STJ110215

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNS3
Gene ID: 3790
Uniprot ID: KCNS3_HUMAN
Immunogen Region: 1-180
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KCNS3 (NP_002243.3).
Immunogen Sequence: MVFGEFFHRPGQDEELVNLN VGGFKQSVDQSTLLRFPHTR LGKLLTCHSEEAILELCDDY SVADKEYYFDRNPSLFRYVL NFYYTGKLHVMEELCVFSFC QEIEYWGINELFIDSCCSNR YQERKEENHEKDWDQKSHDV STDSSFEESSLFEKELEKFD TLRFGQLRKKIWIRMENPAY
Tissue Specificity Detected in whole normal term placental and placental chorionic plate arteries and veins. Detected in syncytiotrophoblast and in blood vessel endothelium within intermediate villi and chorionic plate (at protein level). Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
Function Potassium channel regulatory subunit that modulates the delayed rectifier potassium channel activity of KCNB1 by namely slowing down the deactivation and inactivation time constants. While it does not form functional channel on its own, it can form functional heterotetrameric channels with KCNB1.
Protein Name Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns3
Delayed-Rectifier K(+ Channel Alpha Subunit 3
Delayed-Rectifier Potassium Channel Subunit Kv9.3
Kv9.3
Potassium Voltage-Gated Channel Subfamily S Member 3
Database Links Reactome: R-HSA-1296072
Reactome: R-HSA-381676
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
May Not Reach The Plasma Membrane But Remain In An Intracellular Compartment In The Absence Of Kcnb1
Alternative Antibody Names Anti-Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns3 antibody
Anti-Delayed-Rectifier K(+ Channel Alpha Subunit 3 antibody
Anti-Delayed-Rectifier Potassium Channel Subunit Kv9.3 antibody
Anti-Kv9.3 antibody
Anti-Potassium Voltage-Gated Channel Subfamily S Member 3 antibody
Anti-KCNS3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance