| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Potassium channel subfamily K member 17 channel 4 channel 2 (271-320 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNK17 |
| Gene ID: |
89822 |
| Uniprot ID: |
KCNKH_HUMAN |
| Immunogen Region: |
271-320 aa |
| Specificity: |
TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human KCNK17 at the amino acid range 271-320 |
| Function | K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties. Present in the cardiac conduction system where it may regulate action potential duration and beating frequency of cardiac myocytes. Permeable to other monovalent cations such as Rb(+) and Cs(+). |
| Protein Name | Potassium Channel Subfamily K Member 172p Domain Potassium Channel Talk-2Acid-Sensitive Potassium Channel Protein Task-4Twik-Related Acid-Sensitive K(+ Channel 4Twik-Related Alkaline Ph-Activated K(+ Channel 2Talk-2 |
| Database Links | Reactome: R-HSA-1299361Reactome: R-HSA-5576886 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily K Member 17 antibodyAnti-2p Domain Potassium Channel Talk-2 antibodyAnti-Acid-Sensitive Potassium Channel Protein Task-4 antibodyAnti-Twik-Related Acid-Sensitive K(+ Channel 4 antibodyAnti-Twik-Related Alkaline Ph-Activated K(+ Channel 2 antibodyAnti-Talk-2 antibodyAnti-KCNK17 antibodyAnti-TALK2 antibodyAnti-TASK4 antibodyAnti-UNQ5816 antibodyAnti-PRO19634 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
