Anti-KCNJ6 antibody (1-80) (STJ111976)

SKU:
STJ111976
£112.50 - £524.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNJ6
Gene ID: 3763
Uniprot ID: KCNJ6_HUMAN
Immunogen Region: 1-80
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human KCNJ6 (NP_002231.1).
Immunogen Sequence: MAKLTESMTNVLEGDSMDQD VESPVAIHQPKLPKQARDDL PRHISRDRTKRKIQRYVRKD GKCNVHHGNVRETYRYLTDI
Tissue Specificity Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
Function This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Protein Name G Protein-Activated Inward Rectifier Potassium Channel 2
Girk-2
Bir1
Inward Rectifier K(+ Channel Kir3.2
Katp-2
Potassium Channel - Inwardly Rectifying Subfamily J Member 6
Database Links Reactome: R-HSA-1296041
Reactome: R-HSA-997272
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-G Protein-Activated Inward Rectifier Potassium Channel 2 antibody
Anti-Girk-2 antibody
Anti-Bir1 antibody
Anti-Inward Rectifier K(+ Channel Kir3.2 antibody
Anti-Katp-2 antibody
Anti-Potassium Channel - Inwardly Rectifying Subfamily J Member 6 antibody
Anti-KCNJ6 antibody
Anti-GIRK2 antibody
Anti-KATP2 antibody
Anti-KCNJ7 antibody

Information sourced from Uniprot.org